Author
University of OxfordORCID 0000-0003-1350-3558Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Francis Grafton, Narjes Rohani, Wooi Fang Lim…·Carlo Rinaldi
This study identifies how the polyglutamine tract in the androgen receptor regulates muscle growth and atrophy by altering transcriptional activity and chromatin binding.
Omnia M. Elsharkasy, Charlotte V. Hegeman, Tom A. P. Driedonks…·Olivier G. de Jong
This paper develops a modular strategy for delivering CRISPR-Cas9 via extracellular vesicles using aptamer-based loading and UV-activated cargo release, demonstrating efficient delivery and versatility in Cas9 variants.
Antonio Garcia-Guerra, Chaitra Sathyaprakash, Olivier G. de Jong…·Carlo Rinaldi
This paper introduces CRISPR MiRAGE, a miRNA-sensing guide RNA system that enables tissue-specific gene editing by modulating CRISPR activity based on miRNA signatures.