Author

Oliver Grant-Chapman

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Amit BudhrajaiD· 1 shared Dennis VoroniniD· 1 shared Dixie Brewington· 1 shared Jamila MooreiD· 1 shared Joseph T. OpfermaniD· 1 shared Josi LottiD· 1 shared Lauren Brakefield· 1 shared Peter A. HalliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amit BudhrajaORCID

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Author profile →

1 paper

Recent·Most cited

Mitochondrial Integrated Stress Response Activation Creates a Therapeutic Vulnerability to MCL-1 Inhibition in Acute Myeloid Leukemia

Lauren Brakefield, Amit Budhraja, Peter A. Hall, Dixie Brewington, Jamila Moore, Josi Lott, Yonghui Ni, Dennis Voronin, Oliver Grant-Chapman, Tresor O Mukiza, Tristen Wright, Yong‐Dong Wang, Sandi Radko-Juettner, Shondra M. Pruett‐Miller, Stanley B Pounds, , Joseph T. Opferman

This study identifies co-targeting of MCL-1 and ETC complex I as a synergistic therapy for high-risk AML, showing improved viability reduction and survival in preclinical models.

Cell Death and Disease · Jun 25, 2026Peer-reviewedCancer Biology