Author

Zhixiang Tong

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alessandro OriiD· 1 shared Alex A. PolleniD· 1 shared Alex RogozhnikoviD· 1 shared Alexis L. RohouiD· 1 shared Andy Lash· 1 shared Anne BitoniD· 1 shared Anthony Batarse· 1 shared Anthony Bosshardt· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alessandro OriORCID

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Author profile →

2 papers

Recent·Most cited

A scalable human neuron model of Alzheimer's disease relevant tauopathy reveals mechanisms linking Tau fibrillization to synaptic dysfunction

Joanna Lipka, Xiwei Shan, Qiao Zhang, Przemysław Dutka, Lilian Phu, Matthew C Johnson, Timothy J. Wendorff, Max Adrian, Anne Biton, Dawei Sun, Meena Choi, John G. Moffat, Alexis L. Rohou, Alessandro Ori, Céline Eidenschenk, , Jasvinder K. Atwal

This paper develops scalable human neuron models of Alzheimer's disease to reveal mechanisms linking Tau fibrillization to synaptic dysfunction and identifies therapeutic targets.

bioRxiv · Sep 12, 2026 · PreprintCell Biology

Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease

Kevan D. Shah, Rishi Bedi, Alex Rogozhnikov, Pavan Ramkumar, Zhixiang Tong, Brian G. Rash, Morgan M. Stanton, Jordan M. Sorokin, Cagsar Apaydin, Anthony Batarse, Julia Bergamaschi, Robert M. Blattner, Spencer Brown, Anthony Bosshardt, Carlos Castrillo, , G. Sean Escola

This paper develops an automated system to scale patient-derived brain organoids, revealing consistent donor and batch effects and demonstrating reproducible disease phenotypes in tuberous sclerosis models.

bioRxiv · Aug 26, 2020 · PreprintNeuroscience