A dual MTOR/NAD+ acting gerotherapy
Jinmei Li, Sandeep Kumar, Kirill Miachin, Nicholas L. Bean, Ornella Halawi, Scott M. Lee, Jiwoong Park, Tanya Hans Pierre, Jin‐Hui Hor, Shi‐Yan Ng, K. Wallace, Niklas Rindtorff, Timothy M. Miller, Michael L. Niehoff, Susan A. Farr, , Timothy R. Peterson
This paper identifies BIOIO-1001 as a dual mTOR/NAD+ acting gerotherapy that reduces metabolic derangements, inflammation, and fibrosis in NASH and ALS models.
bioRxiv · Jan 16, 2023 · PreprintGenomics