Author

Oscar Ospina

Johns Hopkins All Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alex Soupir· 1 shared Andrea Mcpherson· 1 shared Brooke L. FridleyiD· 1 shared Elsa Renee FloresiD· 1 shared Eric Welsh· 1 shared Hayley D. AckermaniD· 1 shared James E. Cox· 1 shared John Koomen· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Alex Soupir

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2 papers

Recent·Most cited

spatialMET: an open and scalable framework for spatial metabolomics analysis

Yonatan Ayalew Mekonnen, Oscar Ospina, Vanessa Rubio, Eric Welsh, Reaz Uddin, Hayley D. Ackerman, Alex Soupir, James E. Cox, Brooke L. Fridley, Elsa Renee Flores, John Koomen, Paul A. Stewart

spatialMET provides a scalable, open-source framework for end-to-end spatial metabolomics analysis, identifying spatial domains and differential metabolites in mouse cancer data.

bioRxiv · Sep 3, 2026 · PreprintBioinformatics

Inter-organ communication shapes human metabolic tissue states and resolves anti-diabetic drug response modes in a six-tissue microphysiological system

Marissa I. McGilvrey, Shereen Chew, Mohd Farhan Siddiqui, Ronald Bronson, Merve Uslu, Shicheng Ye, Oscar Ospina, Andrea Mcpherson, Katrina Diel, Matjaz Dogsa, Luther Raechal, Martin Trapečar

This study develops a six-tissue microphysiological system to investigate how inter-organ communication and nutrient conditions influence metabolic tissue states and drug responses to anti-diabetic therapies.

bioRxiv · May 27, 2026 · PreprintBioengineering