Author

P. Auberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Robert· 3 shared A. Jacquel· 2 shared A. R. Martin· 2 shared C. Favreau· 2 shared R. Benhida· 2 shared A. M. Pendergast· 1 shared A. Porterszman· 1 shared A. Puissant· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

G. Robert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual targeting of GPX4 and TXNRD1 triggers eradication of AML cells through induction of apoptosis and ferroptosis

C. Favreau, C. Savy, M. Bourgoin, T. Botton, S. Bailly, F. Granger, C. Birck, M. Zerhouni, E. Kerreneur, A. Vigroux, J. Dussart-Gautheret, M.-L. Arcangeli, T. Cluzeau, A. Porterszman, S. Rocchi, , G. Robert

The paper identifies two compounds that target GPX4 and TXNRD1 to induce apoptosis and ferroptosis in AML cells, effectively eradicating malignant cells while sparing normal hematopoietic cells.

bioRxiv · Apr 3, 2024 · PreprintBiochemistry

MCB-613 exploits a collateral sensitivity in drug-resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1

C. F. Bassil, G. R. Anderson, B. Mayro, K. N. Askin, P. S. Winter, S. Gruber, T. M. Hall, J. P. Hoj, C. Cerda-Smith, H. M. Hutchinson, S. T. Killarney, K. R. Singleton, L. Qin, K. Jubien-Girard, C. Favreau, , K. C. Wood

The paper identifies MCB-613 as a compound that targets KEAP1 in EGFR inhibitor-resistant NSCLC cells, exploiting its selective essentiality through covalent inhibition.

bioRxiv · Jan 17, 2023 · PreprintCancer Biology

HSPA8 chaperone complex drives chaperone-mediated autophagy regulation in acute promyelocytic leukemia differentiation

S. Rafiq, I. Mungure, N. J. Niklaus, S. Mueller, A. Jacquel, G. Robert, P. Auberger, B. E. Torbett, S. Muller, M. P. Tschan, M. Humbert

This study shows that HSPA8 chaperone complex regulates chaperone-mediated autophagy (CMA) during APL differentiation, with CMA downregulation required for neutrophil maturation.

bioRxiv · Aug 7, 2022 · PreprintCancer Biology