Author

P. Balaguer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Grimaldi· 2 shared W. Bourguet· 2 shared A. A. Amato· 1 shared A. Ancelin· 1 shared A. Barducci· 1 shared A. Boulahtouf· 1 shared A. Y. Kuo· 1 shared B. Blumberg· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

M. Grimaldi

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2 papers

Recent·Most cited

2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors

X.-M. Ren, R. C. Chang, Y. Huang, A. A. Amato, C. Carivenc, M. Grimaldi, A. Y. Kuo, P. Balaguer, W. Bourguet, B. Blumberg

This study shows that 2,4-DTBP induces adipogenesis in human MSCs by activating RXR, suggesting it as an obesogen and endocrine disruptor.

bioRxiv · Oct 8, 2022Pharmacology & Toxicology

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

J. Gruszczyk, L. Grandvuillemin, J. Lai-Kee-Him, M. Paloni, C. G. Savva, P. Germain, M. Grimaldi, A. Boulahtouf, H.-S. Kwong, J. Bous, A. Ancelin, C. Bechara, A. Barducci, P. Balaguer, W. Bourguet

The paper presents a cryo-EM structure of the AHR complex bound to a ligand, revealing structural details of its activation mechanism and ligand-binding specificity.

bioRxiv · May 17, 2022Biochemistry