Author

P. C. Woo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Yan· 2 shared H. Cao· 2 shared Y. Li· 2 shared Z. Xu· 2 shared C.-C. Tsang· 1 shared G. Zhang· 1 shared H. Ma· 1 shared H. Xiang· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

A. Yan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A transferrable and integrative type I-F Cascade for heterologous genome editing and transcription modulation

Z. Xu, Y. Li, H. Cao, M. Si, G. Zhang, P. C. Woo, A. Yan

This paper develops a transferrable I-F Cascade system for genome editing and transcription modulation in P. aeruginosa, showing improved efficiency and versatility over Cas9.

bioRxiv · Feb 8, 2021Microbiology

NLRP3 inflammasome contributes to host defense against Talaromyces marneffei infection

H. Ma, J. F.-W. Chan, Y. P. Tan, L. Kui, C.-C. Tsang, S. L. Pei, Y.-L. Lau, P. C. Woo, P. P. Lee

This study shows that NLRP3 inflammasome activation is critical for host defense against Talaromyces marneffei infection by promoting IL-1β production and Th1/Th17 responses.

bioRxiv · Aug 17, 2020Microbiology

Native CRISPR-Cas mediated in situ genome editing reveals the exquisite interplay of resistance mutations in clinical multidrug resistant Pseudomonas aeruginosa

Z. Xu, M. Li, Y. Li, H. Cao, P. C. Woo, H. Xiang, A. Yan

This study uses native CRISPR-Cas genome editing to analyze resistance mechanisms in a multidrug-resistant Pseudomonas aeruginosa strain, revealing synergistic effects between efflux pumps and target mutations.

bioRxiv · Jan 8, 2019 · PreprintMicrobiology