Author

P. Casaccia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Mahajan· 1 shared A. Mela· 1 shared A. Quinones-Hinojosa· 1 shared A. Thomann· 1 shared A. Vidal Ceballos· 1 shared A.-K. Probstel· 1 shared B. C. A. Cree· 1 shared E. Cekanaviciute· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Mahajan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modified histone peptides uniquely tune the material properties of HP1α condensates.

P. Deshpande, E. Prentice, A. Vidal Ceballos, P. Casaccia, S. Elbaum-Garfinkle

This paper shows that H3K9me3 histone peptides modulate the viscoelastic properties of HP1α-DNA condensates in a concentration-dependent manner, linking epigenetic marks to the dynamic behavior of heterochromatin.

bioRxiv · Feb 7, 2024 · PreprintBiophysics

EZH2 inhibition sensitizes IDH1R132H mutant gliomas to histone deacetylase inhibitor.

L. Sprinzen, F. G. Garcia, A. Mela, L. Lei, P. Upadhyayula, A. Mahajan, N. Humala, L. Manier, R. M. Caprioli, A. Quinones-Hinojosa, P. Casaccia, P. Canoll

This study shows that EZH2 inhibition synergizes with HDAC inhibitors to kill IDH1R132H mutant glioma cells by reducing H3K27me3 and increasing H3K27ac.

bioRxiv · Jul 31, 2023Cancer Biology

Multiple sclerosis-associated changes in the composition and immune functions of spore-forming bacteria

E. Cekanaviciute, A.-K. Probstel, A. Thomann, T. Runia, P. Casaccia, I. Katz Sand, E. Crabtree, S. Singh, J. Morrissey, P. Barba, R. Gomez, R. Knight, S. Mazmanian, J. Graves, B. C. A. Cree, , S. Baranzini

This study investigates how spore-forming bacteria in MS patients affect T lymphocyte differentiation and inflammation, showing impaired immunomodulatory responses in vitro.

bioRxiv · Jun 11, 2018Immunology