Author

S. Mazmanian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:metagenomics· 2

Frequent Co-Authors

R. Knight· 4 shared G. Humphrey· 2 shared M. Wang· 2 shared A. A. Aksenov· 1 shared A. Kovtun· 1 shared A. Moradian· 1 shared A. Noto· 1 shared A. T. Nelson· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

R. Knight

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multi-omic analysis along the gut-brain axis points to a functional architecture of autism

J. T. Morton, D.-m. Jin, R. Mills, Y. Shao, G. Rahman, D. McDonald, K. Harold-Berding, B. D. Needham, M. F. Zurita, M. David, O. Averina, A. Kovtun, A. Noto, M. Mussap, M. Wang, , G. Taroncher-Oldenburg

The paper identifies a functional architecture of autism along the gut-brain axis using multi-omic data, revealing microbial and metabolic profiles linked to autism symptoms.

bioRxiv · Feb 25, 2022 · PreprintMicrobiology

Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology

J. A. Griffiths, B. B. Yoo, P. Thuy-Boun, V. Cantu, K. Weldon, C. Challis, M. J. Sweredoski, K. Y. Chan, T. M. Thron, G. Sharon, A. Moradian, G. Humphrey, Q. Zhu, J. Shaffer, D. W. Wolan, , S. Mazmanian

This study activates specific gut neurons in mice to show they influence microbiome structure and gut physiology, including bile acids and fecal output, without brain signals.

bioRxiv · Apr 12, 2021Physiology

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids

R. A. Quinn, A. Vrbanac, A. V. Melnik, K. A. Patras, M. Christy, A. T. Nelson, A. A. Aksenov, A. Tripathi, G. Humphrey, R. da Silva, R. Bussell, T. Thron, M. Wang, F. Vargas, J. Gauglitz, , P. C. Dorrestein

The paper identifies novel conjugated bile acids produced by the microbiome in mice and humans using mass spectrometry and a murine 3D model.

bioRxiv · Jun 3, 2019 · PreprintMicrobiology

Multiple sclerosis-associated changes in the composition and immune functions of spore-forming bacteria

E. Cekanaviciute, A.-K. Probstel, A. Thomann, T. Runia, P. Casaccia, I. Katz Sand, E. Crabtree, S. Singh, J. Morrissey, P. Barba, R. Gomez, R. Knight, S. Mazmanian, J. Graves, B. C. A. Cree, , S. Baranzini

This study investigates how spore-forming bacteria in MS patients affect T lymphocyte differentiation and inflammation, showing impaired immunomodulatory responses in vitro.

bioRxiv · Jun 11, 2018Immunology