Author

P. J. Brouwer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

R. W. Sanders· 3 shared A. B. Ward· 2 shared G. J. de Bree· 2 shared I. Bontjer· 2 shared J. Copps· 2 shared M. J. van Gils· 2 shared A. Aartse· 1 shared A. Antanasijevic· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

R. W. Sanders

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Author profile →

3 papers

Recent·Most cited

A public antibody class recognizes a novel S2 epitope exposed on open conformations of SARS-CoV-2 spike

M. Claireaux, T. G. Caniels, M. de Gast, J. Han, D. Guerra, G. Kerster, B. D. van Schaik, A. Jongejan, A. I. Schriek, M. Grobben, P. J. Brouwer, K. van der Straten, Y. Aldon, J. Capella-Pujol, J. L. Snitselaar, , M. J. van Gils

The paper identifies a novel S2 epitope recognized by a public antibody class in SARS-CoV-2-reactive B cells, which becomes exposed on vaccine-optimized spike proteins.

bioRxiv · Dec 1, 2021Immunology

Infection and transmission of SARS-CoV-2 depends on heparan sulfate proteoglycans

M. Bermejo-Jambrina, J. Eder, T. M. Kaptein, J. L. van Hamme, L. C. Helgers, K. E. Vlaming, P. J. Brouwer, A. P. Vlaar, F. E. H. P. van Baarle, M. Spaargaren, G. J. de Bree, B. M. Nijmeijer, N. A. Kootstra, M. J. van Gils, R. W. Sanders, T. B. H. Geijtenbeek

This study identifies heparan sulfate proteoglycans as SARS-CoV-2 attachment receptors and shows that LMWH blocks infection and transmission.

bioRxiv · Aug 18, 2020Immunology

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

A. Antanasijevic, G. Ueda, J. Copps, P. J. Brouwer, D. Huang, J. D. Allen, C. A. Cottrell, A. Yasmeen, L. M. Sewall, I. Bontjer, T. J. Ketas, H. L. Turner, Z. T. Berndsen, P. J. Klasse, M. Crispin, , A. B. Ward

The paper evaluates de novo-designed two-component nanoparticles for presenting HIV Env trimers, showing improved antibody responses through multivalent display.

bioRxiv · Jan 31, 2020Immunology