The unique three-dimensional arrangement of Macrophage Galactose Lectin enables E. coli LipoPolySaccharides recognition through two distinct interfaces
M. Abbas, M. Maalej, F. Nieto Fabregat, M. Thepaut, J.-p. Kleman, I. Ayala, A. Molinaro, J.-P. Simorre, R. Marchetti, F. Fieschi, C. Laguri
The paper identifies two distinct glycan binding interfaces on Macrophage Galactose Lectin that enable high-affinity recognition of E. coli LipoPolySaccharides, independent of the canonical calcium-dependent site.
bioRxiv · Mar 2, 2023 · PreprintBiophysics