J.-F. Collet

The outer membrane and peptidoglycan layer form a single mechanical device balancing turgor

The peptidoglycan and outer membrane are interconnected layers that cooperate to balance cytoplasmic turgor.

Bacterial cell widening alters periplasmic size and activates envelope stress responses

This study shows that changes in bacterial cell width affect periplasmic thickness and activate the Rcs stress response system through RcsF.

A molecular plugin rescues GroEL/ES substrates from pre-folding oxidation

This study identifies CnoX as a redox quality-control plugin for GroEL, showing it binds outside the substrate-binding site and forms mixed-disulfides with substrates.

YhcB coordinates peptidoglycan and LPS biogenesis with phospholipid synthesis during Escherichia coli cell growth.

This study identifies YhcB as a coordinator of peptidoglycan, LPS, and phospholipid synthesis in E. coli, revealing its role in envelope stability and cell size control.

Disorder is a critical component of lipoprotein sorting in Gram-negative bacteria

The paper identifies intrinsically disordered linkers in lipoproteins essential for their sorting in E. coli, showing that disorder is critical for proper trafficking by the Lol system.

Defining the function of OmpA in the Rcs stress response

This study investigates how OmpA interacts with RcsF in Escherichia coli, revealing that OmpA competes with IgaA for RcsF binding and regulates the Rcs stress response.

Structural insight into the formation of lipoprotein-β-barrel complexes by the β-barrel assembly machinery

The paper reports the crystal structure of BamA in complex with RcsF, revealing a push-and-pull mechanism for RcsF export and providing insights into BAM function and antibiotic development.