Evolution of Human-specific Alleles Protecting Cognitive Function of Grandmothers
S. Saha, N. Khan, T. Comi, A. Verhagen, A. Sasmal, S. Diaz, H. Yu, X. Chen, J. M. Akey, M. Frank, P. Gagneux, A. Varki
The paper investigates human-specific CD33 mutations linked to cognitive protection and Alzheimer's disease resistance, linking them to evolutionary pressures and immune evasion.
bioRxiv · Nov 26, 2021Evolutionary Biology