Author

A. Sasmal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Varki· 2 shared H. Yu· 2 shared X. Chen· 2 shared A. Verhagen· 1 shared C. Dhar· 1 shared D. Xu· 1 shared E. Bandala-Sanchez· 1 shared J. M. Akey· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersEvolutionary Biology

A. Varki

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2 papers

Recent·Most cited

Evolution of Human-specific Alleles Protecting Cognitive Function of Grandmothers

S. Saha, N. Khan, T. Comi, A. Verhagen, A. Sasmal, S. Diaz, H. Yu, X. Chen, J. M. Akey, M. Frank, P. Gagneux, A. Varki

The paper investigates human-specific CD33 mutations linked to cognitive protection and Alzheimer's disease resistance, linking them to evolutionary pressures and immune evasion.

bioRxiv · Nov 26, 2021Evolutionary Biology

Acidosis, Zinc and HMGB1 in Sepsis: A Common Connection Involving Sialoglycan Recognition

S. S. Siddiqui, C. Dhar, V. Sundaramurthy, A. Sasmal, H. Yu, E. Bandala-Sanchez, M. Li, X. Zhang, X. Chen, L. C. Harrison, D. Xu, A. Varki

This study shows that HMGB1 is sequestered by plasma sialoglycoproteins at physiological pH but is released during sepsis when pH and zinc levels drop, leading to immune activation.

Proceedings of the National Academy of Sciences · Mar 3, 2021Peer-reviewedImmunology