The functional landscape of patient derived RNF43 mutations predicts Wnt inhibitor sensitivity
J. Yu, P. A. Bt Mohamed Yuso, P. Goh, N. P. HARMSTON, D. Epstein, D. M. Virshup, B. Madan
This study identifies RNF43 mutations that predict sensitivity to Wnt inhibitors by analyzing their functional impact in vitro and in vivo.
bioRxiv · Mar 25, 2020 · PreprintCancer Biology