Author

P. J. Brighton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:scRNA-seq· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. S. Lucas· 4 shared J. J. Brosens· 4 shared C.-S. Kong· 3 shared A. C. Hanyaloglu· 2 shared P. Vrljicak· 2 shared S. Ott· 2 shared S. Quenby· 2 shared A. Hawkes· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

E. S. Lucas

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4 papers

Recent·Most cited

Spatial targeting of the prostaglandin receptor EP2 to very early endosomes co-ordinates PGE2-mediated cAMP signaling in decidualizing human endometrium

P. J. Brighton, A. R. Walker, O. Mann, C.-S. Kong, E. S. Lucas, P. Vrljicak, J. J. Brosens, A. C. Hanyaloglu

The paper shows that PGE2's spatial targeting to very early endosomes is crucial for coordinating cAMP signaling in decidualizing human endometrium.

bioRxiv · Mar 7, 2024 · PreprintCell Biology

Lack of evidence for functional luteinising hormone chorionic gonadotropin receptors in non-pregnant human endometrial stromal cells

O. N. Mann, C.-S. Kong, E. S. Lucas, J. J. Brosens, A. C. Hanyaloglu, P. J. Brighton

This study investigates LHCGR expression and function in human endometrial stromal cells, finding no functional activity but identifying a small subpopulation with detectable transcripts.

bioRxiv · Jan 5, 2022 · PreprintPharmacology & Toxicology

Characterization of highly proliferative decidual precursor cells during the window of implantation in human endometrium

M. Diniz-da-Costa, C.-S. Kong, K. J. Fishwick, T. Rawlings, P. J. Brighton, A. Hawkes, J. Odendaal, S. Quenby, S. Ott, E. S. Lucas, P. S. Vrljicak, J. J. Brosens

This study identifies highly proliferative decidual precursor cells in human endometrium during implantation, linking their depletion to recurrent pregnancy loss.

bioRxiv · Dec 16, 2020Cell Biology

Clearance of senescent decidual cells by uterine natural killer cells drives endometrial remodeling during the window of implantation

P. J. Brighton, Y. Maruyama, K. Fishwick, P. Vrljicak, S. Tewary, R. Fujihara, J. Muter, E. S. Lucas, T. Yamada, L. Woods, R. Lucciola, Y. H. Lee, S. Takeda, S. Ott, M. Hemberger, , J. J. Brosens

bioRxiv · Aug 4, 2017Cell Biology