A. C. Hanyaloglu

Spatial targeting of the prostaglandin receptor EP2 to very early endosomes co-ordinates PGE2-mediated cAMP signaling in decidualizing human endometrium

The paper shows that PGE2's spatial targeting to very early endosomes is crucial for coordinating cAMP signaling in decidualizing human endometrium.

Lack of evidence for functional luteinising hormone chorionic gonadotropin receptors in non-pregnant human endometrial stromal cells

This study investigates LHCGR expression and function in human endometrial stromal cells, finding no functional activity but identifying a small subpopulation with detectable transcripts.

Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

This study shows that adding a C-terminal tail to the tailless murine GnRHR impairs fertility by reducing FSH production and ovarian follicle development.

Short chain fatty acids enhance expression and activity of the umami taste receptor in enteroendocrine cells via a Gαi/o pathway

This study shows SCFAs enhance umami receptor expression in EECs via Gi/o signaling, improving nutrient sensing without affecting SCFA GPCRs.

Membrane estrogen receptor (GPER) and follicle-stimulating hormone receptor heteromeric complexes promote human ovarian follicle survival

The paper shows that FSHR/GPER heteromers block cAMP-dependent follicle selection and link to poor FSH response and tumor growth in women.

Structural lipids enable the formation of functional oligomers of the eukaryotic purine symporter UapA

The paper investigates how membrane lipids affect the structure and function of the purine transporter UapA, showing that specific lipids stabilize its dimeric form and transport activity.