An integrative approach unveils a distal encounter site for rPTPε and phospho-Src complex formation
N. EswarKumar, C.-H. Yang, S. Tewary, Y.-Q. Yeh, H.-C. Yang, M.-C. Ho
The paper determines the structure of a transient rPTPε and phospho-Src complex using integrative methods, showing a distal interaction site and a mutation-induced disruption of binding.
bioRxiv · Jan 13, 2021Biophysics