Author

P. J. Conn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. M. Niswender· 2 shared C. W. Lindsley· 2 shared A. M. Bender· 1 shared A. Rodriguez· 1 shared B. J. Stansley· 1 shared D. J. Foster· 1 shared F. Nicoletti· 1 shared J. C. O'Neill· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. M. Niswender

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2 papers

Recent·Most cited

Activating mGlu3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus.

S. Dogra, B. J. Stansley, Z. Xiang, W. Qian, R. G. Gogliotti, F. Nicoletti, C. W. Lindsley, C. M. Niswender, M. E. Joffe, P. J. Conn

This study shows that activating mGlu3 receptors in hippocampal pyramidal cells improves cognitive function in mice by inducing metaplastic changes that enhance synaptic plasticity.

bioRxiv · Oct 27, 2020Pharmacology & Toxicology

Discovery of the first selective M4 muscarinic acetylcholine receptor antagonists with in vivo anti-parkinsonian and anti-dystonic efficacy

M. S. Moehle, A. M. Bender, J. W. Dickerson, D. J. Foster, Y. Donsante, W. Peng, Z. K. Bryany, T. M. Bridges, S. Chang, K. J. Watson, J. C. O'Neill, J. L. Engers, L. Peng, A. Rodriguez, C. M. Niswender, , J. M. Rook

This paper discovers the first selective M4 muscarinic acetylcholine receptor antagonists and confirms their anti-parkinsonian and anti-dystonic efficacy in rodent models.

bioRxiv · Oct 12, 2020 · PreprintPharmacology & Toxicology