Author

P. J. Neeson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. Mangiola· 2 shared A. Gifford· 1 shared A. J. Costello· 1 shared A. S. Moore· 1 shared A. Senapati· 1 shared A. T. Papenfuss· 1 shared A. Yuksel· 1 shared B. Pal· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

S. Mangiola

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Author profile →

3 papers

Recent·Most cited

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

C. Mayoh, A. Gifford, R. Terry, L. M. Lau, M. Wong, P. Rao, T. Shai-Hee, F. Saletta, D.-A. Khuong-Quang, V. Qin, M. Mateos, D. Meyran, K. E. Miller, A. Yuksel, E. V. Mould, , P. G Ekert

The paper develops a 15-gene immune signature to identify T-cell infiltration in high-risk paediatric cancers, finding up to 31% of such cancers have infiltrating T-cells.

bioRxiv · Sep 16, 2022 · PreprintCancer Biology

Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis

M. Dinevska, S. S. Widodo, L. Furst, L. Cuzcano, Y. Fang, S. Mangiola, P. J. Neeson, P. K. Darcy, R. G. Ramsay, F. MacKay, S. S. Stylli, T. Mantamadiotis

The paper shows that glioma progression involves changes in immune cell infiltration, extracellular matrix deposition, and signaling heterogeneity, with implications for therapy.

bioRxiv · Dec 5, 2021Cancer Biology

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

S. Mangiola, P. McCoy, M. Modrak, F. S. F. Guimaraes, D. Blashki, R. Stuchbery, S. P. Keam, M. Kerger, K. Chow, C. Nasa, M. Le Page, N. Lister, S. Monard, J. Peters, P. Dundee, , C. M. Hovens

This study uses transcriptome sequencing and multiplex imaging to show that monocytic cells drive prostate cancer progression and immune modulation.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology