Author

S. Mangiola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Pal· 3 shared A. T. Papenfuss· 2 shared P. J. Neeson· 2 shared A. Behren· 1 shared A. Garnham· 1 shared A. J. Costello· 1 shared A. Kallies· 1 shared A. Odainic· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

B. Pal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

S. Mangiola, R. Brown, J. Berthelet, S. Guleria, C. Liyanage, S. Ostrouska, J. Wilcox, M. Merdas, P. F. Larsen, C. Bell, J. Schroder, L. Mielke, J. Mariadason, S. Chang-Hao Tsao, Y. Chen, , B. Pal

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

A multi-organ map of the human immune system across age, sex and ethnicity

S. Mangiola, M. Milton, N. Ranathunga, C. LiWaiSuen, A. Odainic, E. Yang, W. Hutchison, A. Garnham, J. Iskander, B. Pal, V. J. Yadav, F. Rossello, V. Carey, A. Kallies, S. Bedoui, , A. T. Papenfuss

The paper creates a comprehensive immune system map across age, sex, and ethnicity using single-cell RNA sequencing data, revealing immune ageing patterns and ethnic diversity in immune checkpoints.

bioRxiv · Jun 8, 2023 · PreprintImmunology

Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis

M. Dinevska, S. S. Widodo, L. Furst, L. Cuzcano, Y. Fang, S. Mangiola, P. J. Neeson, P. K. Darcy, R. G. Ramsay, F. MacKay, S. S. Stylli, T. Mantamadiotis

The paper shows that glioma progression involves changes in immune cell infiltration, extracellular matrix deposition, and signaling heterogeneity, with implications for therapy.

bioRxiv · Dec 5, 2021Cancer Biology

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

S. Mangiola, P. McCoy, M. Modrak, F. S. F. Guimaraes, D. Blashki, R. Stuchbery, S. P. Keam, M. Kerger, K. Chow, C. Nasa, M. Le Page, N. Lister, S. Monard, J. Peters, P. Dundee, , C. M. Hovens

This study uses transcriptome sequencing and multiplex imaging to show that monocytic cells drive prostate cancer progression and immune modulation.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology