Author

P. Khare

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

D. S. Manickam· 2 shared K. M. Dave· 2 shared Y. S. Kamte· 2 shared A. Dixit· 1 shared A. Kumar· 1 shared A. Tripathi· 1 shared B. Lopez-Gutierrez· 1 shared D. Miller· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

D. S. Manickam

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Effect of homotypic vs. heterotypic interactions on the cellular uptake of extracellular vesicles

J. R. Jhaveri, P. Khare, P. P. Pinky, Y. S. Kamte, M. N. Chandwani, J. Milosevic, N. Abraham, K. M. Dave, S.-y. Zheng, L. O'Donnell, D. S. Manickam

This study compares homotypic and heterotypic EV interactions on uptake in BECs and macrophages, finding membrane fusion dominates uptake in low-pinocytic cells.

bioRxiv · Oct 23, 2023 · PreprintBioengineering

A novel multi-epitope peptide vaccine candidate targeting Hepatitis E virus: an in-silico approach

A. Kumar, U. Sahu, G. Agnihotri, A. Dixit, P. Khare

This paper designs a multi-epitope peptide vaccine against Hepatitis E virus using in-silico methods, showing it is immunogenic, stable, and non-allergic.

bioRxiv · Dec 13, 2022Immunology

Lipidoid nanoparticles increase ATP uptake into hypoxic brain endothelial cells

P. Khare, J. F. Conway, D. Soundara Manickam

This paper demonstrates that lipidoid nanoparticles (LNPs) can deliver ATP to brain endothelial cells, increasing ATP uptake under both normoxic and hypoxic conditions.

bioRxiv · Apr 7, 2022Bioengineering

Development of lipidoid nanoparticles for siRNA delivery to neural cells

P. Khare, K. M. Dave, Y. S. Kamte, M. A. Manoharan, L. A. O'Donnell, D. S. Manickam

This study demonstrates that lipidoid nanoparticles can efficiently and safely deliver siRNA to neural cells, outperforming a commercial transfection agent in terms of safety.

bioRxiv · Jul 28, 2021Bioengineering

Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen

N. G. Bender, P. Khare, J. Martinez, R. E. Tweedell, V. O. Nyasembe, B. Lopez-Gutierrez, A. Tripathi, D. Miller, T. Hamerly, E. M. Vela, R. F. Howard, S. Nsango, R. R. Cobb, M. Harbers, R. R. Dinglasan

The paper evaluates a new malaria transmission-blocking vaccine antigen, UF6b, showing it induces potent antibodies against a key epitope and is immunogenic in mice.

bioRxiv · Nov 29, 2020Immunology

Role of TRPV1 in colonic mucin production and gut microbiota profile

V. Kumar, N. Mahajan, P. Khare, K. K. Kondepudi, M. Bishnoi

This study shows that TRPV1 ablation in rats reduces mucus production and alters gut microbiota, suggesting potential adverse effects of TRPV1-targeted therapies.

bioRxiv · Apr 17, 2020Physiology