D. Miller

Integrated Movement Models for Individual Tracking and Species Distribution Data

This paper introduces an integrated movement model to estimate population-level movement parameters by combining individual tracking and species distribution data, improving accuracy and enabling new population metrics.

Homeostatic macrophages prevent preterm birth and improve neonatal outcomes by mitigating in utero sterile inflammation

The paper shows that M2 macrophages prevent preterm birth and improve neonatal outcomes by reducing in utero sterile inflammation in mice.

Using big sequencing data to identify chronic SARS-Coronavirus-2 infections

The paper identifies chronic SARS-CoV-2 infections by analyzing phylogenetic clades with identical metadata and finds that chronic-like clades predict adaptive mutations in circulating variants.

Aryl Hydrocarbon Receptor Suppresses Eosinophilic Esophagitis Responses through OVOL1 and SPINK7

This study identifies OVOL1 as a regulator of SPINK7 expression in eosinophilic esophagitis, showing AHR activation enhances SPINK7 and barrier function while IL-4 and IL-13 inhibit this pathway.

Visible-Light Optical Coherence Tomography Fibergraphy of the Tree Shrew Retinal Ganglion Cell Axon Bundles

This study uses vis-OCTF and TSA to image tree shrew retinal ganglion cell axon bundles in vivo, quantifying their dimensions and showing changes with distance from the optic nerve head.

Siglecs in the Porcine Oviduct and Sialylated Ligands on Sperm: Roles in the Formation of the Sperm Reservoir

This study identifies Siglecs and sialylated ligands on porcine sperm that may mediate immune tolerance in the oviduct, contributing to sperm reservoir formation.

A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate

This paper introduces a 3D-printed flow-cell device for on-grid affinity purification of cryo-EM samples directly from lysate, aiming to improve sample preparation efficiency.

An oviduct glycan increases sperm lifespan by diminishing ubiquinone and production of reactive oxygen species

This study identifies an oviduct glycan that extends sperm lifespan by reducing ubiquinone precursor levels and reactive oxygen species production in porcine sperm.

The single-cell atlas of the murine reproductive tissues during preterm labor

This study uses scRNA-seq to create a single-cell atlas of murine reproductive tissues during infection-induced preterm labor, identifying gene expression signatures and intercellular communication changes.

Integrating Subclonal Response Heterogeneity to Define Cancer Organoid Therapeutic Sensitivity

The paper evaluates individual patient-derived cancer organoids using optical metabolic imaging to predict therapeutic response and identify subclonal populations and resistance mechanisms.

Crystal Structures of Ferritin Grown by the Microbatch Method in the Presence of Agarose and Electric Field Shows Enhanced Metal Binding

The paper reports crystal structures of Horse Spleen Ferritin grown using a novel agarose microbatch method with and without electric field, showing enhanced metal binding.

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.

This study identifies CX-5461 as a TOP2B inhibitor with selective activity in high-risk neuroblastoma but highlights safety concerns due to TOP2B off-target effects.

Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen

The paper evaluates a new malaria transmission-blocking vaccine antigen, UF6b, showing it induces potent antibodies against a key epitope and is immunogenic in mice.

A short course of Tofacitinib sustains the immunoregulatory effect of CTLA4-Ig in presence of inflammatory cytokines and promotes long-term survival of murine cardiac allografts

This study shows that combining Tofacitinib with CTLA4-Ig improves cardiac allograft survival by reducing effector T cells and increasing regulatory T cells in mice.

Identification and characterisation of a phospholipid scramblase in the malaria parasite Plasmodium falciparum

The paper identifies and characterizes a phospholipid scramblase in Plasmodium falciparum, showing its activity and expression but not essentiality for erythrocyte invasion.

Laser-activated drug implant for controlled release to the posterior segment of the eye

This paper develops a laser-activated drug implant for controlled release in the posterior eye, showing in vitro and in vivo drug release kinetics and safety.

Experimental methodologies can affect pathogenicity of Batrachochytrium salamandrivorans infections

The paper evaluates how variations in experimental methods affect disease-induced mortality in eastern newts infected with Bsal, finding that passage duration, exposure method, and habitat influence outcomes.

Open-Source Food: Nutrition, Toxicology, and Availability of Wild Edible Greens in the East Bay

The paper assesses the safety, nutrition, and availability of wild edible greens in urban areas, finding they are abundant, nutritious, and safe to eat after rinsing, despite soil contamination.

Rhamnolipids from Pseudomonas aeruginosa disperse the Biofilms of Sulfate-Reducing Bacteria

This study shows that Pseudomonas aeruginosa supernatants, containing rhamnolipids, effectively disperse biofilms of sulfate-reducing bacteria and other microbes.

Computational Analysis of Lifespan Experiment Reproducibility

This study assesses the reproducibility of C. elegans lifespan experiments and finds that small effects are rarely detected due to low statistical power, suggesting the need for larger sample sizes.