Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype
J. R. Barrett, D. Pipini, N. D. Wright, A. J. R. Cooper, G. Gorini, D. Quinkert, A. M. Lias, H. Davies, C. Rigby, M. Aleshnick, B. G. Williams, W. J. Bradshaw, N. G. Paterson, T. Martinson, P. Kirtley, , S. J. Draper
The paper characterizes human antibodies against PfRH5, identifies key features of potent inhibitors, and demonstrates their prophylactic potential against malaria.
Cell · Sep 1, 2024Peer-reviewedImmunology