Author

P. Kumthekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Assay:clinical cohort / trial· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Hawkins-Daarud· 3 shared K. R. Swanson· 3 shared L. S. Hu· 3 shared P. Whitmire· 3 shared S. K. Johnston· 3 shared A. B. Porter· 2 shared J. B. Rubin· 2 shared K. M. Egan· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Hawkins-Daarud

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Author profile →

4 papers

Recent·Most cited

De-novo purine biosynthesis is a major driver of chemoresistance in glioblastoma

J. M. Shireman, F. Atashi, G. Lee, E. Ali, M. Saathoff, C. Park, S. Baiswala, J. Miska, M. Lesniak, J. C. David, R. Stupp, P. Kumthekar, C. Horbinski, I. Ben-Sahar, A. U. Ahmed

This study identifies de-novo purine biosynthesis as a driver of chemoresistance in glioblastoma and shows that targeting it with Mycophenolate Mofetil can enhance TMZ efficacy.

Brain · Apr 14, 2021Peer-reviewedCancer Biology

Sex Differences in Predictors of Seizure in Contrast-Enhancing Gliomas at Clinical Presentation: A Network Approach

S. K. Johnston, A. Khurana, P. Whitmire, S. Ranjbar, A. Sharma, A. Hawkins-Daarud, J. B. Rubin, A. B. Porter, P. D. Canoll, K. Egan, L. S. Hu, M. M. Mrugala, P. Kumthekar, K. R. Swanson

The paper uses a machine learning model to predict seizure risk in glioma patients at presentation, finding sex, tumor size, and age as significant predictors.

bioRxiv · Jul 23, 2019 · PreprintCancer Biology

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: a Multi-disciplinary Team-based, Multifactorial Analytical Approach

S. K. Johnston, P. Whitmire, S. C. Massey, P. Kumthekar, A. B. Porter, N. Raghunand, L. F. Gonzalez-Cuyar, M. M. Mrugala, A. Hawkins-Daarud, P. R. Jackson, L. S. Hu, J. N. Sarkaria, L. Wang, R. A. Gatenby, K. M. Egan, , K. R. Swanson

The paper introduces the ENDURES consortium to study extreme survivors of glioblastoma by integrating clinical data and creating patient-specific tumor models.

bioRxiv · Nov 4, 2018 · PreprintCancer Biology

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients

P. Whitmire, C. R. Rickertsen, A. Hawkins-Daarud, E. Carrasco, J. Lorence, G. De Leon, L. Curtin, S. Bayless, K. Clark-Swanson, N. C. Peeri, C. Corpuz, C. P. Lewis-de los Angeles, B. R. Bendok, L. Gonzalez-Cuyar, S. Vora, , K. R. Swanson

This study identifies sex-specific predictors of survival in glioblastoma patients using MR imaging and clinical data.

bioRxiv · Sep 25, 2018Cancer Biology