P. D. Canoll

A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

The paper identifies a metabolic vulnerability in specific glioma cell states that can be targeted with GPX4 inhibitors to induce ferroptosis.

Immune Response following FLASH and Conventional Radiation in Diffuse Midline Glioma (DMG)

This study compares the immune response in diffuse midline glioma after FLASH and conventional radiation using single-cell RNA sequencing and flow cytometry, finding differences in type 1 interferon signaling over time.

SARS-CoV-2 infection results in lasting and systemic perturbations post recovery

This study compares short- and long-term systemic responses to SARS-CoV-2 and IAV in golden hamsters, finding persistent inflammation in olfactory tissues post-recovery.

Sex Differences in Predictors of Seizure in Contrast-Enhancing Gliomas at Clinical Presentation: A Network Approach

The paper uses a machine learning model to predict seizure risk in glioma patients at presentation, finding sex, tumor size, and age as significant predictors.

CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas

This study shows that CD8+ T-cells mediate immunoediting in murine gliomas, affecting genomic stability and immune evasion.