Author

P. MacAry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

F. Samsudin· 2 shared G. S. Anand· 2 shared P. J. Bond· 2 shared A. Boags· 1 shared A. Schmidtchen· 1 shared A. T. Shivgan· 1 shared C. Pedebos· 1 shared G. Petruk· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

F. Samsudin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade

F. Samsudin, P. Raghuvamsi, G. Petruk, M. Puthia, J. Petrlova, P. MacAry, G. S. Anand, A. Schmidtchen, P. J. Bond

This study shows SARS-CoV-2 spike protein binds LPS, which may enhance immune activation via TLR4, with conserved binding sites across variants.

bioRxiv · Oct 29, 2021Microbiology

Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein

L. Zuzic, F. Samsudin, A. T. Shivgan, P. V. Raghuvamsi, J. K. Marzinek, A. Boags, C. Pedebos, N. K. Tulsian, J. Warwicker, P. MacAry, M. Crispin, S. Khalid, G. S. Anand, P. J. Bond

This study identifies a novel cryptic pocket on the SARS-CoV-2 spike protein using molecular dynamics simulations and validates its druggable potential through experimental methods.

bioRxiv · May 5, 2021Biophysics