P. Radler

Self-organisation of mortal filaments: the role of FtsZ treadmilling in bacterial division ring formation

The paper shows that FtsZ treadmilling drives nematic ordering in bacterial cells, enabling division ring formation through local dissolution of misaligned filaments.

Stress-induced clustering of the UPR sensor IRE1 is driven by disordered regions within its ER lumenal domain

This study shows that IRE1's ER lumenal domain forms dynamic condensates stabilized by membranes and unfolded polypeptides, which are essential for its clustering and signaling.

Chiral and nematic phases of flexible active filaments

The paper investigates how filament flexibility, density, and chirality influence the formation of chiral and nematic phases in FtsZ filaments during bacterial cell division.

In vitro reconstitution of divisome activation

This study uses biochemical and imaging methods to investigate how FtsA activates the bacterial divisome by switching between polymer and monomer states, revealing its role in FtsZ dynamics and FtsN recruitment.

Computational analysis of filament polymerization dynamics in cytoskeletal networks

The paper introduces an automated image analysis workflow to study polymerization dynamics of cytoskeletal filaments using time-lapse microscopy data.

FtsZ assembles the bacterial cell division machinery by a diffusion-and-capture mechanism

The paper shows FtsZ treadmilling recruits divisome proteins via diffusion-and-capture, explaining how the Z-ring dynamically assembles the bacterial cell division machinery.