Author

P. Caldas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:bacteria (other)· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. Loose· 4 shared C. Sommer· 2 shared J. Brugues· 2 shared M. Lopez-Pelegrin· 2 shared P. Radler· 2 shared B. C. de Jong· 1 shared C. Campos· 1 shared C. J. Meehan· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiophysics

M. Loose

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species

E. Machado, S. Vasconcellos, L. Gomes, M. Catanho, J. Ramos, L. de Carvalho, T. Goldenberg, M. Dalcolmo, P. Redner, P. Caldas, C. Campos, M. C. Lourenco, E. Lasunskaia, V. Mussi, L. Spinasse, , P. Suffys

This study analyzes 665 Mycobacterium kansasii complex strains to identify unique and shared genomic signatures, revealing lineage splits, virulence factors, and drug resistance mechanisms.

bioRxiv · Feb 14, 2024Evolutionary Biology

In vitro reconstitution of divisome activation

P. Radler, N. Baranova, P. Caldas, C. Sommer, M. Lopez-Pelegrin, D. Michalik, M. Loose

This study uses biochemical and imaging methods to investigate how FtsA activates the bacterial divisome by switching between polymer and monomer states, revealing its role in FtsZ dynamics and FtsN recruitment.

bioRxiv · Nov 8, 2021 · PreprintBiochemistry

Spatial Variation of Microtubule Depolymerization in Large Asters Suggests Regulation by MAP Depletion

K. Ishihara, F. Decker, P. Caldas, J. Pelletier, M. Loose, J. Brugues, T. Mitchison

The paper measures microtubule depolymerization rates in Xenopus egg extract asters and finds higher rates in the interior compared to the periphery, suggesting regulation by MAP depletion.

Molecular Biology of the Cell · Apr 19, 2021Peer-reviewedCell Biology

Computational analysis of filament polymerization dynamics in cytoskeletal networks

P. Caldas, P. Radler, C. Sommer, M. Loose

The paper introduces an automated image analysis workflow to study polymerization dynamics of cytoskeletal filaments using time-lapse microscopy data.

bioRxiv · Nov 12, 2019 · PreprintBiophysics

ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics

P. Caldas, M. Lopez-Pelegrin, D. J. G. Pearce, N. B. Budanur, J. Brugues, M. Loose

This study shows ZapA stabilizes FtsZ filament bundles in vitro without affecting treadmilling speed, explaining how Z-ring architecture is maintained.

bioRxiv · Mar 19, 2019Biophysics