Author

P. S. Zammit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cell Biology· 1

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Pruller· 2 shared M. Ganassi· 2 shared A. E. Decleves· 1 shared A. Frustaci· 1 shared A. Kozlov· 1 shared A. M. Shah· 1 shared A. Protti· 1 shared A. Tassin· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

J. Pruller

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Author profile →

3 papers

Recent·Most cited

An in silico FSHD muscle fibre for modelling DUX4 dynamics and predicting the impact of therapy

M. V. Cowley, J. Pruller, M. Ganassi, P. S. Zammit, C. R. S. Banerji

The paper develops an in silico model of FSHD muscle fibers to simulate DUX4 dynamics and predict therapy outcomes based on single-cell RNA sequencing data.

bioRxiv · Dec 12, 2022Cell Biology

Interplay between mitochondria and reactive oxygen and nitrogen species in metabolic adaptation to hypoxia in facioscapulohumeral muscular dystrophy: potential therapeutic targets.

P. Heher, M. Ganassi, A. Weidinger, E. N. Engquist, J. Pruller, T. H. Nguyen, A. Tassin, A. E. Decleves, K. Mamchaoui, J. Grillari, A. Kozlov, P. S. Zammit

This paper investigates how mitochondrial reactive oxygen and nitrogen species (RONS) metabolism contributes to oxidative stress in FSHD, showing that mitochondria-targeted antioxidants are more effective in rescuing pathology.

bioRxiv · Sep 8, 2021 · PreprintPathology

Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies

D. Brayson, A. Frustaci, R. Verardo, C. Chimenti, M. A. Russo, R. Hayward, S. M. Ahmad, G. Vizcay-Barrena, A. Protti, P. S. Zammit, C. G. dos Remedios, E. Ehler, A. M. Shah, C. M. Shanahan

This study shows prelamin A accumulation drives inflammation in both inherited and acquired cardiomyopathies, suggesting potential treatment strategies targeting inflammation.

bioRxiv · Nov 28, 2018Pathology