Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
Kevin C. Lister, Calvin Wong, Sonali Uttam, Marc Parisien, Patricia Stecum, Nicole Brown, Weihua Cai, David Ho-Tieng, Mehdi Hooshmandi, Ning Gu, Mehdi Amiri, Francis Beaudry, Seyed Mehdi Jafarnejad, Diana Tavares‐Ferreira, Nikhil Nageshwar Inturi, , Arkady Khoutorsky
This study shows that translational control in spinal cord neurons, particularly in inhibitory and PV+ interneurons, significantly influences gene expression and pain hypersensitivity during the chronic phase of neuropathic pain.
eLife · Mar 31, 2026Peer-reviewedNeuroscience