Author

Pauline Rouan

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Guy M. LippensiD· 2 shared Alain R. BaulardiD· 1 shared Alessia MichelottiiD· 1 shared Astrid Lenne· 1 shared Camille GrosseiD· 1 shared Christophe GuilhotiD· 1 shared Cyril CharlieriD· 1 shared Cyril GaudiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Guy M. LippensORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Exploiting Vitamin B6 Dependency: BVL3572S Inhibits HisC and AlaA to Kill Mycobacterium tuberculosis

Zainab Edoo, Astrid Lenne, Camille Grosse, Marie Devaere, Marion Michel, Guillaume Caron, Ernesto Anoz‐Carbonell, Kamel Djaout, Rosangela Frita, Cyril Gaudin, Line Hofmann, Sophie Lecher, Véronique Mégalizzi, Alessia Michelotti, David Rengel, , Alain R. Baulard

This paper identifies BVL3572S as a compound that inhibits HisC and AlaA in Mtb, causing metabolic stress and showing synergy with existing drugs.

Cell chemical biology · Aug 1, 2026Peer-reviewedMicrobiology

Estimating flux dynamics from metabolite concentration time courses with dynafluxr

Sergueï Sokol, Svetlana A. Dubiley, Pauline Rouan, Cyril Charlier, Guy M. Lippens, Pierre Millard

The paper introduces dynafluxr, a method to estimate metabolic flux dynamics from metabolite concentration time courses using constrained B-splines, showing it works well on both simulated and experimental data.

bioRxiv · Jul 22, 2025 · PreprintSystems Biology