Measuring nonapoptotic caspase activity with a transgenic reporter in mice
PETER J. NICHOLLS, Thomas F. Pack, Nikhil M. Urs, Sunil Kumar, Yang Zhou, Gabriel Ichim, Joshua D. Ginzel, Gábor Turu, Evan Calabrese, Wendy L. Roberts, Ping Fan, Valeriy G. Ostapchenko, Monica S. Guzman Lenis, Flávio H. Beraldo, Jiřı́ Hatina, , Marc G. Caron
The paper develops a transgenic mouse model with a fluorescent caspase activity reporter to quantify nonapoptotic caspase activity in rodent brains and demonstrates its use in studying neurophysiological and stress-related effects.
eNeuro · Sep 1, 2022Peer-reviewedNeuroscience