BiochemistryCell Death and DiseasePeer-reviewed
Proteasome Inhibition Enhances Lysosome-mediated Targeted Protein Degradation
Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram Vangala…·Senthil K. Radhakrishnan
This paper shows that combining proteasome inhibitors with lysosome-targeted degradation enhances cancer cell death by exploiting an adaptive autophagy response.
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