Author

Ahmed M. Elshazly

Kafrelsheikh UniversityORCID 0000-0003-0353-1643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Senthil K. RadhakrishnaniD· 2 shared Adolfo Gabriele MauroiD· 1 shared Fadi N. SalloumiD· 1 shared Hisashi HaradaiD· 1 shared Janakiram Reddy VangalaiD· 1 shared Janakiram Vangala· 1 shared Nayyerehalsadat HosseiniiD· 1 shared Piyusha P. Pagare· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Senthil K. RadhakrishnanORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 24, 2026

Tumor-selective Mcl1 degradation by AUTAC uncouples antitumor efficacy from cardiotoxicity

Ahmed M. Elshazly, Janakiram Reddy Vangala, Adolfo Gabriele Mauro…·Senthil K. Radhakrishnan

This paper shows that AUTAC selectively degrades Mcl1 in tumors without affecting the heart, improving antitumor efficacy while avoiding cardiotoxicity.

1 citation

mouseexperimental assay

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BiochemistryCell Death and DiseasePeer-reviewedMay 11, 2026

Proteasome Inhibition Enhances Lysosome-mediated Targeted Protein Degradation

Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram Vangala…·Senthil K. Radhakrishnan

This paper shows that combining proteasome inhibitors with lysosome-targeted degradation enhances cancer cell death by exploiting an adaptive autophagy response.

7 citationstop 2%

humanproteomics

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