Author

Nayyerehalsadat Hosseini

Virginia Commonwealth UniversityORCID 0000-0003-0443-9371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Senthil K. RadhakrishnaniD· 2 shared Shanwei SheniD· 2 shared Afroditi SotiriouiD· 1 shared Ahmed M. ElshazlyiD· 1 shared Alexandros C. DimopoulosiD· 1 shared Ana BanitoiD· 1 shared Andrew Stewart PoklepoviciD· 1 shared Angeliki M. Stamatouli· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Senthil K. RadhakrishnanORCID

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2 papers

Recent·Most cited

BiochemistryCell Death and DiseasePeer-reviewedMay 11, 2026

Proteasome Inhibition Enhances Lysosome-mediated Targeted Protein Degradation

Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram Vangala…·Senthil K. Radhakrishnan

This paper shows that combining proteasome inhibitors with lysosome-targeted degradation enhances cancer cell death by exploiting an adaptive autophagy response.

7 citationstop 2%

humanproteomics

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Cancer BiologyNature CommunicationsPeer-reviewedNov 5, 2025

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma

Konstantinos V. Floros, Carter K. Fairchild, Jinxiu Li…·Anthony C. Faber

This study shows that inhibiting SUMOylation with TAK-981 stabilizes cBAF complexes and disrupts the SS18::SSX-driven transcriptome in synovial sarcoma, leading to tumor inhibition.

13 citations

humanmouse

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