Author

Victoria L. Neely

Virginia Commonwealth UniversityORCID 0009-0004-8409-1823Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Hisashi HaradaiD· 2 shared Senthil K. RadhakrishnaniD· 2 shared Ahmed M. ElshazlyiD· 1 shared Bin HuiD· 1 shared Boxiao DingiD· 1 shared Bradford E. WindleiD· 1 shared Eziafa OduahiD· 1 shared Janakiram Vangala· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Hisashi HaradaORCID

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2 papers

Recent·Most cited

Proteasome Inhibition Enhances Lysosome-mediated Targeted Protein Degradation

Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram Vangala, Shanwei Shen, Victoria L. Neely, Xiaoyan Hu, Piyusha P. Pagare, Hisashi Harada, Steven Grant, Senthil K. Radhakrishnan

This paper shows that combining proteasome inhibitors with lysosome-targeted degradation enhances cancer cell death by exploiting an adaptive autophagy response.

Cell Death and Disease · May 11, 2026Peer-reviewedBiochemistry

Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

Kranthi Kumar Chougoni, Victoria L. Neely, Boxiao Ding, Eziafa Oduah, Vianna T. Lam, Bin Hu, Jennifer E. Koblinski, Bradford E. Windle, Swati Palit Deb, Sumitra Deb, Jorge J. Nieva, Senthil K. Radhakrishnan, Hisashi Harada, Steven R. Grossman

This study shows proteasome inhibitors are more effective against NSCLC cells with mutant p53 by inducing oxidative stress and mitochondrial apoptosis, suggesting a new therapeutic strategy.

Cancer Research Communications · Sep 20, 2024Peer-reviewedCancer Biology