Author

Q. Q. Gao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. E. Peter· 4 shared A. A. Sarshad· 3 shared A. E. Murmann· 3 shared E. T. Bartom· 3 shared M. Hafner· 3 shared W. Putzbach· 3 shared A. Haluck-Kangas· 2 shared M. Patel· 2 shared

Activity by Year

2017-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersCancer Biology

M. E. Peter

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4 papers

Recent·Most cited

CD95/Fas ligand mRNA is toxic to cells

W. Putzbach, A. Haluck-Kangas, Q. Q. Gao, A. A. Sarshad, E. T. Bartom, A. M. Stults, A. S. Qadir, M. Hafner, M. E. Peter

The paper shows that full-length CD95L mRNA is toxic to cells and induces apoptosis through sRNA processing independent of Dicer and Drosha, suggesting a new role for RNAi in cell fate regulation.

bioRxiv · Sep 14, 2018Cancer Biology

6mer seed toxicity in tumor suppressive microRNAs

Q. Q. Gao, W. E. Putzbach, A. E. Murmann, S. Chen, A. A. Sarshad, J. M. Peter, E. T. Bartom, M. Hafner, M. E. Peter

The paper identifies 6mer seed sequences in miRNAs that are toxic to cancer cells, showing that tumor suppressive miRNAs use these toxic seeds to kill cancer cells.

bioRxiv · Aug 31, 2018Cell Biology

Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells

A. E. Murmann, Q. Q. Gao, W. Putzbach, M. Patel, E. T. Bartom, C. Law, B. Bridgeman, S. Chen, K. M. McMahon, C. S. Thaxton, M. E. Peter

The paper shows that siRNAs based on CAG TNRs are toxic to cancer cells and slow tumor growth in a mouse model without toxicity.

bioRxiv · Jan 12, 2018Cancer Biology

Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

W. Putzbach, Q. Q. Gao, M. Patel, S. van Dongen, A. Haluck-Kangas, A. A. Sarshad, E. Bartom, K.-Y. A. Kim, D. M. Scholtens, M. Hafner, J. C. Zhao, A. E. Murmann, M. E. Peter

The paper shows that many si/shRNAs targeting CD95 or CD95L induce cancer cell death via an off-target mechanism called DISE by eliminating survival genes.

bioRxiv · Sep 14, 2017Cancer Biology