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Q. W. C. Ho

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Approach:statistical model· 1

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D. L. Silver· 1 shared E. G. Y. Chew· 1 shared F. T. Torta· 1 shared J. N. Foo· 1 shared M. Chua· 1 shared M. M. Lian· 1 shared M. R. Wenk· 1 shared O. Stelmashenko· 1 shared

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1 shared paperBiochemistry

D. L. Silver

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintFeb 28, 2021

Destabilization of β-cell FIT2 by saturated fatty acids contribute to ER stress and diabetes

X. Zheng, Q. W. C. Ho, M. Chua…·Y. Ali

This study shows that saturated fatty acids reduce β-cell lipid droplets by destabilizing FIT2, leading to ER stress and diabetes, while FIT2 overexpression protects against these effects.

DOI 10.1101/2021.02.28.433270

mousebulk RNA-seq

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