Evolutionary landscape of oral microbiome over 100,000 years
Ling Zhong, Heng Li, Shuting Xia, Shichang Xie, Raffaella Bianucci, Shengkai Li, Sirirak Supa-amornkul, Camilla Speller, Qing Shi, Yinqiu Cui, Huilin Yang, Mark Achtman, Zhemin Zhou
This study traces the evolutionary changes in the human oral microbiome over 102,400 years, revealing co-evolution with cultural and medical transitions and highlighting shifts in microbial ecology and antimicrobial resistance.
bioRxiv · Nov 1, 2025 · PreprintMicrobiology