A. C. Fagre

Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2

This study shows Jamaican fruit bats are poorly susceptible to SARS-CoV-2 but develop a regulatory T cell-like immune response when transduced with human ACE2, leading to lung infection without overt disease.

SARS-CoV-2 infects multiple species of North American deer mice and causes clinical disease in the California mouse

This study shows SARS-CoV-2 infects multiple North American deer mice and causes clinical disease in California mice, suggesting potential wildlife reservoirs and co-morbidity factors for severe COVID-19.

Viral diversity and zoonotic risk in endangered species

The paper examines the relationship between endangered species status and viral diversity, finding lower virus diversity in endangered species despite higher research effort, possibly due to sampling biases.

Sampling strategies and pre-pandemic surveillance gaps for bat coronaviruses

This study analyzes bat coronavirus sampling strategies and identifies pre-pandemic surveillance gaps that may hinder understanding of zoonotic coronavirus origins.

Exploring the mosquito-arbovirus network: a survey of vector competence experiments

This study reviews mosquito-arbovirus competence experiments, finding most potential mosquito-virus combinations are untested, limiting predictive modeling of vector-virus networks.

The Global Virome in One Network (VIRION): an atlas of vertebrate-virus associations

The paper creates VIRION, a comprehensive database of vertebrate-virus associations, and demonstrates its utility for studying microbiology, ecology, and evolution.

A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2

This paper shows that PT150, a glucocorticoid and androgen receptor antagonist, reduces SARS-CoV-2 replication and inflammatory responses in Syrian hamsters.