R. A. Zubarev

This study shows that everolimus, a rapamycin analog, uniquely affects the ubiquitin-proteasome system by increasing ubiquitin levels and altering polyubiquitination patterns, distinct from its analogs.

The paper introduces PISA-REX, a high-throughput proteomics method combining redox, expression, and solubility analysis, and demonstrates its application in studying interferon responses in human monocytes and mice.

The paper uses SpotLight proteomics to identify antibody sequences specific to deamidated human serum albumin, revealing insights into protein clearance and neurodegeneration prevention.

This study identifies DOPA residues in collagen as redox-active components that provide radical scavenging capacity, outperforming their precursors and ascorbic acid.

This study identifies hundreds of novel GALNT1 substrates using proteomics tools, revealing preferences for Thr residues and Pro at positions +3 and +4, and implicating GALNT1 in diverse biological pathways.

This study shows that redox regulation of PTPN22 via cysteine 129 affects T cell-dependent autoimmune inflammation severity in mice.

The paper introduces the PISA assay, which improves throughput and sensitivity in profiling factor-induced proteome stability changes by avoiding curve fitting and enabling parameter variation analysis.

The paper identifies RNA editing events at the proteome level in Drosophila melanogaster using shotgun proteomics and a customized database.