Author

M. A. Kennedy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

R. C. Auer· 3 shared B. L. Stoddard· 2 shared C. Tanese de Souza· 2 shared D. Baker· 2 shared L.-H. Tai· 2 shared R. D. Kibler· 2 shared S. Lee· 2 shared A. A. Ananth· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

R. C. Auer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Design of four component T=4 tetrahedral, octahedral, and icosahedral protein nanocages through programmed symmetry breaking

S. Lee, R. D. Kibler, Y. Hsia, A. J. Borst, A. Philomin, M. A. Kennedy, B. L. Stoddard, D. Baker

The paper designs T=4 protein nanocages with tetrahedral, octahedral, and icosahedral symmetries using pseudo-symmetrization of trimeric building blocks, resulting in structures with distinct subunits and interfaces.

bioRxiv · Jun 16, 2023 · PreprintBiochemistry

Stepwise design of pseudosymmetric protein hetero-oligomers

R. D. Kibler, S. Lee, M. A. Kennedy, B. I. M. Wicky, S. M. Lai, M. M. Kostelic, X. Li, C. M. Chow, L. Carter, V. H. Wysocki, B. L. Stoddard, D. Baker

The paper introduces a method to design pseudosymmetric protein hetero-oligomers by redesigning symmetric homo-oligomers and recombining them to form new hetero-oligomers with high structural specificity.

bioRxiv · Apr 7, 2023 · PreprintBiochemistry

An easily adopted murine model of distal pancreatectomy for investigating immunotherapy efficacy in resectable pancreatic adenocarcinoma

K. E. Baxter, C. Tanese de Souza, L.-H. Tai, P. Yaghini, M. Daneshmand, J. C. Bell, B. D. Lichty, M. A. Kennedy, R. C. Auer

This paper develops a surgically resectable murine model of pancreatic adenocarcinoma to test immunotherapy efficacy in preclinical studies.

bioRxiv · Mar 17, 2020 · PreprintCancer Biology

A Comprehensive Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood

M. Market, G. Tennakoon, J. Ng, M. Scaffidi, C. Tanese de Souza, M. A. Kennedy, R. C. Auer

This paper evaluates NK cell phenotype and function in whole blood versus cryopreserved PBMCs, finding significant differences in receptor expression.

bioRxiv · Feb 3, 2020Immunology

Molecular basis of P major human rotavirus VP8* domain interactions with histo-blood group antigens

S. Xu, Y. Liu, M. Tan, W. Zhong, D. Zhao, X. Jiang, M. A. Kennedy

This paper uses NMR to determine how P[8] and P[6] rotavirus VP8* domains bind to different histo-blood group antigens, revealing structural differences that may explain their distinct host ranges and evolutionary adaptations.

bioRxiv · Jan 4, 2019Biochemistry

Sepsis Increases Perioperative Metastases In A Murine Model

L.-H. Tai, A. A. Ananth, R. Seth, A. Alkayyal, J. Zhang, C. T. de Souza, P. Staibano, M. A. Kennedy, R. C. Auer

This study shows that sepsis during surgery increases metastases in mice, while hemorrhagic shock and hypothermia do not.

bioRxiv · May 31, 2017Cancer Biology