Desmoglein-1 coordinates cell proliferation and actin dynamics to promote epidermal morphogenesis.
Brieanna Jarrell, R. DiDominicis, Marihan Hegazy, Mariana De Niz, Robert M. Harmon, Xin Tong, Jennifer Leigh Koetsier, Dongmei Wang, Matthias Rübsam, Carien M. Niessen, Rui Yi, Lisa Marie Godsel, Ziyou Ren, Kathleen Janee Green
This study uses scRNA-seq to show Dsg1 coordinates cell proliferation and actin dynamics to drive epidermal morphogenesis through a Dsg1-Nck1-N-WASP axis.
bioRxiv · Sep 30, 2026 · PreprintCell Biology