Matthias Rübsam

This study uses scRNA-seq to show Dsg1 coordinates cell proliferation and actin dynamics to drive epidermal morphogenesis through a Dsg1-Nck1-N-WASP axis.

This study identifies local mechanical heterogeneity as the driver of epidermal cell delamination through force balance changes and actomyosin remodeling in keratinocytes.

The paper shows that tissue mechanics control epithelial multilayering by regulating cell differentiation and movement strategies in the developing mouse epidermis.

This study identifies spectrin as a key organizer of the keratinocyte actomyosin cortex that coordinates cell shape and signaling during epidermal differentiation.

This study identifies a postnatal skin barrier defect in Suox-/- mice, linking sulfite oxidase deficiency to epidermal dysfunction and early mortality.