Kathleen Janee Green

The paper investigates immune infiltration and triad formation in early melanoma progression using spatial transcriptomics, finding increased immune engagement in Stage I lesions compared to Stage 0.

This study uses scRNA-seq to show Dsg1 coordinates cell proliferation and actin dynamics to drive epidermal morphogenesis through a Dsg1-Nck1-N-WASP axis.

This study identifies the desmosome-intermediate filament network as critical for mechano-response in epidermis, showing its regulation by PP2A-mediated phosphorylation of desmoplakin.

The paper identifies Ect2 as a binding partner of desmoplakin, showing its role in maintaining RhoA activity at cell junctions and linking it to Carvajal disease pathology.

This study investigates how stress exacerbates metabolic and oxidative stress in heterozygous Darier disease, leading to disrupted intercellular adhesion and skin lesions.

This paper performs RNA-seq on skin samples from three acantholytic diseases to identify shared transcriptomic features and mechanisms of pathogenesis.

This study shows that miR-205 modulates the mechanical properties of hair follicle stem cells and progenitors to promote hair regeneration.