Lisa Marie Godsel

This study uses scRNA-seq to show Dsg1 coordinates cell proliferation and actin dynamics to drive epidermal morphogenesis through a Dsg1-Nck1-N-WASP axis.

The paper identifies Ect2 as a binding partner of desmoplakin, showing its role in maintaining RhoA activity at cell junctions and linking it to Carvajal disease pathology.

This study investigates how stress exacerbates metabolic and oxidative stress in heterozygous Darier disease, leading to disrupted intercellular adhesion and skin lesions.

This paper performs RNA-seq on skin samples from three acantholytic diseases to identify shared transcriptomic features and mechanisms of pathogenesis.