Author

R. Gifford

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kumar· 1 shared C. Shema Mugisha· 1 shared J. E. Eschbach· 1 shared K. Davis· 1 shared K. Tenneti· 1 shared M. Kvaratskhelia· 1 shared S. Kutluay· 1 shared T. Dinh· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

A. Kumar

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1 paper

Recent·Most cited

Emergence of compensatory mutations reveal the importance of electrostatic interactions between HIV-1 integrase and genomic RNA

C. Shema Mugisha, T. Dinh, A. Kumar, K. Tenneti, J. E. Eschbach, K. Davis, R. Gifford, M. Kvaratskhelia, S. Kutluay

This study identifies compensatory mutations that restore HIV-1 integrase-gRNA binding and infectivity, revealing the role of electrostatic interactions in this process and their impact on allosteric inhibitor sensitivity.

bioRxiv · Dec 16, 2021Microbiology