Regulation of intracellular signaling and neuron function by Bardet-Biedl Syndrome proteins in patient-specific iPSC-derived neurons
L. Wang, Y. Liu, G. Stratigopoulos, S. Panigrahi, L. Sui, C. A. Leduc, H. J. Glover, M. C. De Rosa, L. C. Burnett, D. J. Williams, L. Shang, R. Goland, S. H. Tsang, S. Wardlaw, D. Egli, , R. L. Leibel
This study investigates how BBS mutations affect neuron function and signaling in iPSC-derived neurons, identifying impaired ciliary function and signaling pathways related to energy homeostasis.
bioRxiv · Oct 29, 2020Cell Biology